Inhibition of the Hepatic Uptake of <sup>99m</sup>Tc-Tetrofosmin Using an Organic Cation Transporter Blocker

Inhibition of the Hepatic Uptake of <sup>99m</sup>Tc-Tetrofosmin Using an Organic Cation Transporter Blocker

The accumulation of high levels of <sup>99m</sup>Tc-tetrofosmin (<sup>99m</sup>Tc-TF) in the hepatobiliary system can lead to imaging artifacts and interference with diagnosis. The present study investigated the transport mechanisms of <sup>99m</sup>Tc-TF and atte...

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Bibliographic Details
Main Authors: Kodai Nishi, Masato Kobayashi, Minori Kikuchi, Asuka Mizutani, Yuka Muranaka, Ikumi Tamai, Keiichi Kawai, Takashi Kudo
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Pharmaceutics
Subjects:
<sup>99m</sup>Tc-tetrofosmin
small-animal SPECT/CT
hepatic uptake
transport mechanism
OCT1
Online Access:https://www.mdpi.com/1999-4923/13/7/1073

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