Depletion of UDP-Glucose and UDP-Galactose Using a Degron System Leads to Growth Cessation of Leishmania major.
Interconversion of UDP-glucose (UDP-Glc) and UDP-galactose (UDP-Gal) by the UDP-Glc 4´-epimerase intimately connects the biosynthesis of these two nucleotide sugars. Their de novo biosynthesis involves transformation of glucose-6-phosphate into glucose-1-phosphate by the phosphoglucomutase and subse...
Main Authors: | Sebastian Damerow, Carolin Hoppe, Giulia Bandini, Patricia Zarnovican, Falk F R Buettner, Carsten G K Lüder, Michael A J Ferguson, Françoise H Routier |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-11-01
|
Series: | PLoS Neglected Tropical Diseases |
Online Access: | http://europepmc.org/articles/PMC4631452?pdf=render |
Similar Items
-
Correction: Depletion of UDP-Glucose and UDP-Galactose Using a Degron System Leads to Growth Cessation of Leishmania major.
by: Sebastian Damerow, et al.
Published: (2016-01-01) -
UDP-galactose:globoside galactosyltransferase in murine kidney.
by: O Koul, et al.
Published: (1990-12-01) -
UDP-galactose 4'-epimerase activities toward UDP-Gal and UDP-GalNAc play different roles in the development of Drosophila melanogaster.
by: Jennifer M I Daenzer, et al.
Published: (2012-01-01) -
Elucidation of substrate specificity in Aspergillus nidulans UDP-galactose-4-epimerase.
by: Sean A Dalrymple, et al.
Published: (2013-01-01) -
Study the specificity of UDP-Sugar pyrophosphorylase using galactose and glucose analogues
by: Wen-Cheng Chen, et al.
Published: (2012)