Tumor infiltrating lymphocytes expanded from pediatric neuroblastoma display heterogeneity of phenotype and function.
Adoptive transfer of ex vivo expanded tumor infiltrating lymphocytes (TILs) has led to clinical benefit in some patients with melanoma but has not demonstrated convincing efficacy in other solid cancers. Whilst the presence of TILs in many types of cancer is often associated with better clinical pro...
Main Authors: | Marina Ollé Hurtado, Jolien Wolbert, Jonathan Fisher, Barry Flutter, Sian Stafford, Jack Barton, Neha Jain, Giuseppe Barone, Yvonne Majani, John Anderson |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0216373 |
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