The effects of traditional fermented beverages on ethanol, ethyl glucuronide and ethyl sulphate levels

Abstract Background Traditional beverages such as şalgam, boza, kımız and kefir are frequently being consumed in Turkey. During the production of these beverages fermentation provides long time bio-preservation due to protective effects of ethanol, a product of microorganisms’ metabolism. Especially...

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Main Authors: Ali Rıza Tümer, Aykut Lale, Mukaddes Gürler, Mahmut Şerif Yıldırım, Ayşe Derya Kaynak, Ramazan Akçan
Format: Article
Language:English
Published: SpringerOpen 2018-04-01
Series:Egyptian Journal of Forensic Sciences
Subjects:
Online Access:http://link.springer.com/article/10.1186/s41935-018-0064-8
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spelling doaj-50173dc353144578b16363a0d6e4a6612020-11-25T01:17:02ZengSpringerOpenEgyptian Journal of Forensic Sciences2090-59392018-04-01811510.1186/s41935-018-0064-8The effects of traditional fermented beverages on ethanol, ethyl glucuronide and ethyl sulphate levelsAli Rıza Tümer0Aykut Lale1Mukaddes Gürler2Mahmut Şerif Yıldırım3Ayşe Derya Kaynak4Ramazan Akçan5Department of Forensic Medicine, Hacettepe University Medical FacultyDepartment of Forensic Medicine, Hacettepe University Medical FacultyDepartment of Medical Biochemistry, Hacettepe University Medical FacultyDepartment of Forensic Medicine, Hacettepe University Medical FacultyDepartment of Forensic Medicine, Hacettepe University Medical FacultyDepartment of Forensic Medicine, Hacettepe University Medical FacultyAbstract Background Traditional beverages such as şalgam, boza, kımız and kefir are frequently being consumed in Turkey. During the production of these beverages fermentation provides long time bio-preservation due to protective effects of ethanol, a product of microorganisms’ metabolism. Especially in traffic controls and in rehabilitation process of alcoholic patients, fermented beverages may cause confusion since it may be linked with false positivity of ethanol and ethanol metabolite tests. The present study aims to assess blood ethanol and urine ethanol metabolite levels after consumption of traditional fermented beverages. Method Twelve participants consumed 300 mL standardized homemade traditional şalgam, boza, kımız and kefir. Blood samples were collected before and after (at 45th min) consumption and urine samples were collected before and after (at 4th hour) consumption from the participants. The samples of these four beverages and the blood samples were analyzed using headspace gas chromatography for ethanol levels, and urine samples were analyzed with liquid chromatography tandem mass spectrometry for ethyl-glucuronide and ethyl-sulphate levels. Results Ethanol levels in şalgam, boza, kımız, and kefir samples, used at the present study, were 80.02 mg/dl, 30.02 mg/dl, 57.83 mg/dl and 6.07 mg/dl, respectively. After consumption of beverages, blood ethanol levels were negative for all analyzed samples. No statistically significant correlation was found between initial and post-consumption ethyl-glucuronide and ethyl-sulphate levels.http://link.springer.com/article/10.1186/s41935-018-0064-8Blood alcohol levelsUrinary ethylglucuronideUrinary ethylsulphateFermented beveragesEthanol
collection DOAJ
language English
format Article
sources DOAJ
author Ali Rıza Tümer
Aykut Lale
Mukaddes Gürler
Mahmut Şerif Yıldırım
Ayşe Derya Kaynak
Ramazan Akçan
spellingShingle Ali Rıza Tümer
Aykut Lale
Mukaddes Gürler
Mahmut Şerif Yıldırım
Ayşe Derya Kaynak
Ramazan Akçan
The effects of traditional fermented beverages on ethanol, ethyl glucuronide and ethyl sulphate levels
Egyptian Journal of Forensic Sciences
Blood alcohol levels
Urinary ethylglucuronide
Urinary ethylsulphate
Fermented beverages
Ethanol
author_facet Ali Rıza Tümer
Aykut Lale
Mukaddes Gürler
Mahmut Şerif Yıldırım
Ayşe Derya Kaynak
Ramazan Akçan
author_sort Ali Rıza Tümer
title The effects of traditional fermented beverages on ethanol, ethyl glucuronide and ethyl sulphate levels
title_short The effects of traditional fermented beverages on ethanol, ethyl glucuronide and ethyl sulphate levels
title_full The effects of traditional fermented beverages on ethanol, ethyl glucuronide and ethyl sulphate levels
title_fullStr The effects of traditional fermented beverages on ethanol, ethyl glucuronide and ethyl sulphate levels
title_full_unstemmed The effects of traditional fermented beverages on ethanol, ethyl glucuronide and ethyl sulphate levels
title_sort effects of traditional fermented beverages on ethanol, ethyl glucuronide and ethyl sulphate levels
publisher SpringerOpen
series Egyptian Journal of Forensic Sciences
issn 2090-5939
publishDate 2018-04-01
description Abstract Background Traditional beverages such as şalgam, boza, kımız and kefir are frequently being consumed in Turkey. During the production of these beverages fermentation provides long time bio-preservation due to protective effects of ethanol, a product of microorganisms’ metabolism. Especially in traffic controls and in rehabilitation process of alcoholic patients, fermented beverages may cause confusion since it may be linked with false positivity of ethanol and ethanol metabolite tests. The present study aims to assess blood ethanol and urine ethanol metabolite levels after consumption of traditional fermented beverages. Method Twelve participants consumed 300 mL standardized homemade traditional şalgam, boza, kımız and kefir. Blood samples were collected before and after (at 45th min) consumption and urine samples were collected before and after (at 4th hour) consumption from the participants. The samples of these four beverages and the blood samples were analyzed using headspace gas chromatography for ethanol levels, and urine samples were analyzed with liquid chromatography tandem mass spectrometry for ethyl-glucuronide and ethyl-sulphate levels. Results Ethanol levels in şalgam, boza, kımız, and kefir samples, used at the present study, were 80.02 mg/dl, 30.02 mg/dl, 57.83 mg/dl and 6.07 mg/dl, respectively. After consumption of beverages, blood ethanol levels were negative for all analyzed samples. No statistically significant correlation was found between initial and post-consumption ethyl-glucuronide and ethyl-sulphate levels.
topic Blood alcohol levels
Urinary ethylglucuronide
Urinary ethylsulphate
Fermented beverages
Ethanol
url http://link.springer.com/article/10.1186/s41935-018-0064-8
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