P2X7 Receptors in Neurodegeneration: Potential Therapeutic Applications From Basic to Clinical Approaches
Purinergic receptors play important roles in central nervous system (CNS), where the bulk of these receptors are implicated in neuroinflammatory responses and regulation of cellular function of neurons, microglial and astrocytes. Within the P2X receptor family, P2X7 receptor is generally known for i...
Main Authors: | Paul R. Territo, Hamideh Zarrinmayeh |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-04-01
|
Series: | Frontiers in Cellular Neuroscience |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fncel.2021.617036/full |
Similar Items
-
P2X7 receptor signaling during adult hippocampal neurogenesis
by: Hannah C Leeson, et al.
Published: (2019-01-01) -
Does Cholinergic Stimulation Affect the P2X7 Receptor-Mediated Dye Uptake in Mast Cells and Macrophages?
by: Dilyara Nurkhametova, et al.
Published: (2020-10-01) -
Chronic administration of P2X7 receptor antagonist JNJ-47965567 delays disease onset and progression, and improves motor performance in ALS SOD1G93A female mice
by: Cristina Ruiz-Ruiz, et al.
Published: (2020-10-01) -
Editorial: P2X7 as Common Therapeutic Target in Brain Diseases
by: Tobias Engel, et al.
Published: (2021-04-01) -
Purinergic–Glycinergic Interaction in Neurodegenerative and Neuroinflammatory Disorders of the Retina
by: Laszlo G. Harsing, et al.
Published: (2021-06-01)