Bone marrow CD73+ mesenchymal stem cells display increased stemness in vitro and promote fracture healing in vivo

Bone marrow CD73+ mesenchymal stem cells display increased stemness in vitro and promote fracture healing in vivo

Mesenchymal stem cells (MSCs) are multipotent and considered to be of great potential for regenerative medicine. We could show recently (Breitbach, Kimura et al. 2018) that a subpopulation of MSCs as well as sinusoidal endothelial cells (sECs) in the bone marrow (BM) of CD73-EGFP reporter mice could...

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Bibliographic Details
Main Authors: Kenichi Kimura, Martin Breitbach, Frank A. Schildberg, Michael Hesse, Bernd K. Fleischmann
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Bone Reports
Subjects:
Mesenchymal stem cells
In vitro differentiation potential
Fracture healing
Endothelial cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2352187221003909

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