Molecules linked to Ras signaling as therapeutic targets in cardiac pathologies

Molecules linked to Ras signaling as therapeutic targets in cardiac pathologies

Highlights The Ras (Rat Sarcoma) gene family is a group of small G proteins Ras is regulated by growth factors and neurohormones affecting cardiomyocyte growth and hypertrophy Ras directly affects cardiomyocyte physiological and pathological hypertrophy Genetic alterations of Ras and its pathways re...

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Bibliographic Details
Main Authors: Manuel Ramos-Kuri, Sri Harika Meka, Fabio Salamanca-Buentello, Roger J. Hajjar, Larissa Lipskaia, Elie R. Chemaly
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Biological Research
Subjects:
Ras-opathies
H-Ras gene
K-Ras gene
Ras pathway
Physiological hypertrophy
Pathological hypertrophy
Online Access:https://doi.org/10.1186/s40659-021-00342-6

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