Interaction of Phenol-Soluble Modulins with Phosphatidylcholine Vesicles

Several members of the staphylococcal phenol-soluble modulin (PSM) peptide family exhibit pronounced capacities to lyse eukaryotic cells, such as neutrophils, monocytes, and erythrocytes. This is commonly assumed to be due to the amphipathic, α-helical structure of PSMs, giving PSMs detergent-like c...

Full description

Bibliographic Details
Main Authors: Anthony C. Duong, Gordon Y. C. Cheung, Michael Otto
Format: Article
Language:English
Published: MDPI AG 2012-07-01
Series:Pathogens
Subjects:
Online Access:http://www.mdpi.com/2076-0817/1/1/3