Comparison of free conjunctival autograft versus amniotic membrane transplantation for pterygium surgery
Purpose: To compare the recurrence rate and surgical outcomes of amniotic membrane transplantation (AMT) and free conjunctival autograft (CAT) for pterygium surgery. Methods: In this prospective study, 60 patients with primary pterygium were randomly assigned to two groups of CAT or AMT and were com...
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doaj-5066f6a194dc4e6db7c2e5372f9a150a2021-04-02T13:59:40ZengWolters Kluwer Medknow PublicationsJournal of Current Ophthalmology2452-23252017-12-01294282286Comparison of free conjunctival autograft versus amniotic membrane transplantation for pterygium surgeryMitra Akbari0Reza Soltani-Moghadam1Ramin Elmi2Ehsan Kazemnejad3Eye Research Center, Department of Ophthalmology, Guilan University of Medical Sciences, Rasht, Iran; Eye Research Center, Amir-Al-Momenin Hospital, Rasht, Guilan, Iran; Corresponding author.Eye Research Center, Department of Ophthalmology, Guilan University of Medical Sciences, Rasht, Iran; Eye Research Center, Amir-Al-Momenin Hospital, Rasht, Guilan, IranLegal Medicine Organization, Rasht, Guilan, IranEye Research Center, Department of Ophthalmology, Guilan University of Medical Sciences, Rasht, Iran; Eye Research Center, Amir-Al-Momenin Hospital, Rasht, Guilan, IranPurpose: To compare the recurrence rate and surgical outcomes of amniotic membrane transplantation (AMT) and free conjunctival autograft (CAT) for pterygium surgery. Methods: In this prospective study, 60 patients with primary pterygium were randomly assigned to two groups of CAT or AMT and were compared in terms of recurrence rate, mean healing time of corneal epithelial defects, the mean level of inflammation, and complications. Results: The mean ± SD age of patients was 48.98 ± 9.8 years (range, 27â71 years). 73.3% were men, and 26.7% were women. The groups did not differ with respect to demographic characteristics (P > 0.05). Patients were followed for an average of 12.6 ± 1.3 months. The recurrence rates were 6.7% and 3.3% in the AMT and CAT groups, respectively (P > 0.05). Comparison of mean inflammation score showed higher inflammation in the AMT group in the first, third, and sixth postoperative month (P < 0.05). Mean healing times of corneal epithelial defects were 2.5 ± 0.572 and 2.67 ± 0.479 days in the CAT and AMT groups, respectively (P = 0.173). Conclusions: No significant complication was observed during or after both surgical methods. No statistically significant difference was seen in visual acuity changes and epithelial healing in CAT and AMT groups, but more inflammation and recurrence rate were seen in AMT group. Keywords: Pterygium surgery, Conjunctival autograft, Amniotic membrane transplantationhttp://www.sciencedirect.com/science/article/pii/S2452232517300859 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mitra Akbari Reza Soltani-Moghadam Ramin Elmi Ehsan Kazemnejad |
spellingShingle |
Mitra Akbari Reza Soltani-Moghadam Ramin Elmi Ehsan Kazemnejad Comparison of free conjunctival autograft versus amniotic membrane transplantation for pterygium surgery Journal of Current Ophthalmology |
author_facet |
Mitra Akbari Reza Soltani-Moghadam Ramin Elmi Ehsan Kazemnejad |
author_sort |
Mitra Akbari |
title |
Comparison of free conjunctival autograft versus amniotic membrane transplantation for pterygium surgery |
title_short |
Comparison of free conjunctival autograft versus amniotic membrane transplantation for pterygium surgery |
title_full |
Comparison of free conjunctival autograft versus amniotic membrane transplantation for pterygium surgery |
title_fullStr |
Comparison of free conjunctival autograft versus amniotic membrane transplantation for pterygium surgery |
title_full_unstemmed |
Comparison of free conjunctival autograft versus amniotic membrane transplantation for pterygium surgery |
title_sort |
comparison of free conjunctival autograft versus amniotic membrane transplantation for pterygium surgery |
publisher |
Wolters Kluwer Medknow Publications |
series |
Journal of Current Ophthalmology |
issn |
2452-2325 |
publishDate |
2017-12-01 |
description |
Purpose: To compare the recurrence rate and surgical outcomes of amniotic membrane transplantation (AMT) and free conjunctival autograft (CAT) for pterygium surgery. Methods: In this prospective study, 60 patients with primary pterygium were randomly assigned to two groups of CAT or AMT and were compared in terms of recurrence rate, mean healing time of corneal epithelial defects, the mean level of inflammation, and complications. Results: The mean ± SD age of patients was 48.98 ± 9.8 years (range, 27â71 years). 73.3% were men, and 26.7% were women. The groups did not differ with respect to demographic characteristics (P > 0.05). Patients were followed for an average of 12.6 ± 1.3 months. The recurrence rates were 6.7% and 3.3% in the AMT and CAT groups, respectively (P > 0.05). Comparison of mean inflammation score showed higher inflammation in the AMT group in the first, third, and sixth postoperative month (P < 0.05). Mean healing times of corneal epithelial defects were 2.5 ± 0.572 and 2.67 ± 0.479 days in the CAT and AMT groups, respectively (P = 0.173). Conclusions: No significant complication was observed during or after both surgical methods. No statistically significant difference was seen in visual acuity changes and epithelial healing in CAT and AMT groups, but more inflammation and recurrence rate were seen in AMT group. Keywords: Pterygium surgery, Conjunctival autograft, Amniotic membrane transplantation |
url |
http://www.sciencedirect.com/science/article/pii/S2452232517300859 |
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