Monitoring ATP dynamics in electrically active white matter tracts

Monitoring ATP dynamics in electrically active white matter tracts

In several neurodegenerative diseases and myelin disorders, the degeneration profiles of myelinated axons are compatible with underlying energy deficits. However, it is presently impossible to measure selectively axonal ATP levels in the electrically active nervous system. We combined transgenic exp...

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Bibliographic Details
Main Authors: Andrea Trevisiol, Aiman S Saab, Ulrike Winkler, Grit Marx, Hiromi Imamura, Wiebke Möbius, Kathrin Kusch, Klaus-Armin Nave, Johannes Hirrlinger
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-04-01
Series:eLife
Subjects:
ATP
axon
myelin
imaging
Online Access:https://elifesciences.org/articles/24241

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