A Single-Cell RNA Sequencing Study Reveals Cellular and Molecular Dynamics of the Hippocampal Neurogenic Niche

A Single-Cell RNA Sequencing Study Reveals Cellular and Molecular Dynamics of the Hippocampal Neurogenic Niche

Adult neurogenesis in the murine dentate gyrus occurs in a specialized microenvironment that sustains the generation of neurons during life. To fully understand adult neurogenesis, it is essential to determine the neural stem cell (NSC) and progenitor developmental stages, their molecular determinan...

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Bibliographic Details
Main Authors: Benedetta Artegiani, Anna Lyubimova, Mauro Muraro, Johan H. van Es, Alexander van Oudenaarden, Hans Clevers
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Cell Reports
Subjects:
adult neurogenesis
dentate gyrus
single cell RNA sequencing
neural stem cells
neural progenitors
microglia
hippocampal niche
aging
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717317023

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