Mettl14-mediated m6A modification modulates neuron apoptosis during the repair of spinal cord injury by regulating the transformation from pri‐mir‐375 to miR-375

Mettl14-mediated m6A modification modulates neuron apoptosis during the repair of spinal cord injury by regulating the transformation from pri‐mir‐375 to miR-375

Abstract Background Spinal cord injury (SCI) is a disabling disorder, resulting in neurological impairments. This study investigated the mechanism of methyltransferase-like 14 (Mettl14) on apoptosis of spinal cord neurons during SCI repair by mediating pri-microRNA (miR) dependent N6-methyladenosine...

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Bibliographic Details
Main Authors: Haoyu Wang, Jing Yuan, Xiaoqian Dang, Zhibin Shi, Wenrui Ban, Dong Ma
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Cell & Bioscience
Subjects:
Spinal cord injury
m6A modification
Mettl14
RASD1
miR-375
Pri‐mir‐375
Online Access:https://doi.org/10.1186/s13578-020-00526-9

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