Pregnancy and childbirth with Shereshevsky–Turner syndrome, established at 12 years of age
The article presents a personal observation of the course of pregnancy and childbirth in a patient with a typical form of gonadal dysgenesis (ShereshevskyTurner syndrome, karyotype 45,X0/46,XY in the ratio of clones 1:1). The diagnosis was established at 12 years of age during an examination for gro...
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IP Berlin A.V.
2020-12-01
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| Series: | Гинекология |
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| Online Access: | https://gynecology.orscience.ru/2079-5831/article/viewFile/34862/pdf |
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doaj-50d17c9c9e74465faecef7e011280a022021-01-26T09:11:52ZrusIP Berlin A.V. Гинекология2079-56962079-58312020-12-01226909210.26442/20795696.2020.6.20040754031Pregnancy and childbirth with Shereshevsky–Turner syndrome, established at 12 years of ageEvgeny S. Mikhaylin0Lada A. Ivanova1Mariya M. Shilo2Igor V. Berlev3Maternity Hospital №10; Mechnikov North-Western State Medical University; People’s Friendship University of RussiaMaternity Hospital №10; Mechnikov North-Western State Medical UniversityMechnikov North-Western State Medical UniversityMechnikov North-Western State Medical UniversityThe article presents a personal observation of the course of pregnancy and childbirth in a patient with a typical form of gonadal dysgenesis (ShereshevskyTurner syndrome, karyotype 45,X0/46,XY in the ratio of clones 1:1). The diagnosis was established at 12 years of age during an examination for growth retardation and lack of signs of puberty. Given the presence of a 46,XY clone in the karyotype, a high risk of malignization of dysgenetic gonads, laparoscopy and gonadectomy were performed at 12 years of age. Pregnancy occurred after preparation of the endometrium with estrogens and progestogens, as a result of the first in vitro fertilization attempt with a donor egg and her husbands sperm, occurred against the background of hormonal support with the threat of termination of pregnancy and hypercoagulation. At 34 weeks, there was a premature detachment of placenta, in connection with which she was delivered by cesarean section.https://gynecology.orscience.ru/2079-5831/article/viewFile/34862/pdfprimary amenorrheaminorsgonadal digenesisshereshevsky–turner syndromein vitro fertilizationoocyte donationclinical caseinfertility |
| collection |
DOAJ |
| language |
Russian |
| format |
Article |
| sources |
DOAJ |
| author |
Evgeny S. Mikhaylin Lada A. Ivanova Mariya M. Shilo Igor V. Berlev |
| spellingShingle |
Evgeny S. Mikhaylin Lada A. Ivanova Mariya M. Shilo Igor V. Berlev Pregnancy and childbirth with Shereshevsky–Turner syndrome, established at 12 years of age Гинекология primary amenorrhea minors gonadal digenesis shereshevsky–turner syndrome in vitro fertilization oocyte donation clinical case infertility |
| author_facet |
Evgeny S. Mikhaylin Lada A. Ivanova Mariya M. Shilo Igor V. Berlev |
| author_sort |
Evgeny S. Mikhaylin |
| title |
Pregnancy and childbirth with Shereshevsky–Turner syndrome, established at 12 years of age |
| title_short |
Pregnancy and childbirth with Shereshevsky–Turner syndrome, established at 12 years of age |
| title_full |
Pregnancy and childbirth with Shereshevsky–Turner syndrome, established at 12 years of age |
| title_fullStr |
Pregnancy and childbirth with Shereshevsky–Turner syndrome, established at 12 years of age |
| title_full_unstemmed |
Pregnancy and childbirth with Shereshevsky–Turner syndrome, established at 12 years of age |
| title_sort |
pregnancy and childbirth with shereshevsky–turner syndrome, established at 12 years of age |
| publisher |
IP Berlin A.V. |
| series |
Гинекология |
| issn |
2079-5696 2079-5831 |
| publishDate |
2020-12-01 |
| description |
The article presents a personal observation of the course of pregnancy and childbirth in a patient with a typical form of gonadal dysgenesis (ShereshevskyTurner syndrome, karyotype 45,X0/46,XY in the ratio of clones 1:1). The diagnosis was established at 12 years of age during an examination for growth retardation and lack of signs of puberty. Given the presence of a 46,XY clone in the karyotype, a high risk of malignization of dysgenetic gonads, laparoscopy and gonadectomy were performed at 12 years of age. Pregnancy occurred after preparation of the endometrium with estrogens and progestogens, as a result of the first in vitro fertilization attempt with a donor egg and her husbands sperm, occurred against the background of hormonal support with the threat of termination of pregnancy and hypercoagulation. At 34 weeks, there was a premature detachment of placenta, in connection with which she was delivered by cesarean section. |
| topic |
primary amenorrhea minors gonadal digenesis shereshevsky–turner syndrome in vitro fertilization oocyte donation clinical case infertility |
| url |
https://gynecology.orscience.ru/2079-5831/article/viewFile/34862/pdf |
| work_keys_str_mv |
AT evgenysmikhaylin pregnancyandchildbirthwithshereshevskyturnersyndromeestablishedat12yearsofage AT ladaaivanova pregnancyandchildbirthwithshereshevskyturnersyndromeestablishedat12yearsofage AT mariyamshilo pregnancyandchildbirthwithshereshevskyturnersyndromeestablishedat12yearsofage AT igorvberlev pregnancyandchildbirthwithshereshevskyturnersyndromeestablishedat12yearsofage |
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