Macrophages Respond Rapidly to Ototoxic Injury of Lateral Line Hair Cells but Are Not Required for Hair Cell Regeneration

Macrophages Respond Rapidly to Ototoxic Injury of Lateral Line Hair Cells but Are Not Required for Hair Cell Regeneration

The sensory organs of the inner ear contain resident populations of macrophages, which are recruited to sites of cellular injury. Such macrophages are known to phagocytose the debris of dying cells but the full role of macrophages in otic pathology is not understood. Lateral line neuromasts of zebra...

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Bibliographic Details
Main Authors: Mark E. Warchol, Angela Schrader, Lavinia Sheets
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Cellular Neuroscience
Subjects:
zebrafish
macrophage
lateral line
hair cell
regeneration
ototoxicity
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2020.613246/full

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