Altered DNA methylation of glycolytic and lipogenic genes in liver from obese and type 2 diabetic patients
Objective: Epigenetic modifications contribute to the etiology of type 2 diabetes. Method: We performed genome-wide methylome and transcriptome analysis in liver from severely obese men with or without type 2 diabetes and non-obese men to discover aberrant pathways underlying the development of insu...
Main Authors: | Henriette Kirchner, Indranil Sinha, Hui Gao, Maxwell A. Ruby, Milena Schönke, Jessica M. Lindvall, Romain Barrès, Anna Krook, Erik Näslund, Karin Dahlman-Wright, Juleen R. Zierath |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-03-01
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Series: | Molecular Metabolism |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2212877815002343 |
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