Cytomegalovirus infection in primiparous pregnant women and their neonates
Cytomegaloviurs (CMV) is the most frequent cause of congenital infection in humans. In various parts of the world the prevalence of antibodies to CMV ranges from 40-100%. The prevalence of primary infection with CMV in pregnant Iranian women and risk of congenital CMV infection in their neonates are...
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Tehran University of Medical Sciences
2002-07-01
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doaj-513bd06428f3482cbe80036a4b26c0f82020-11-25T03:39:31ZengTehran University of Medical SciencesActa Medica Iranica0044-60252002-07-01403136139Cytomegalovirus infection in primiparous pregnant women and their neonates"Siadati ANoorbakhsh SGhazi FRimaz ShMonavari SHRCytomegaloviurs (CMV) is the most frequent cause of congenital infection in humans. In various parts of the world the prevalence of antibodies to CMV ranges from 40-100%. The prevalence of primary infection with CMV in pregnant Iranian women and risk of congenital CMV infection in their neonates are unknown. To Determine the prevalence of CMV infection in primiparous pregnant (youner) women and incidence rate of cangenital CMV infection among preterm and full-term infants borned from these women, in serum of 164 primigravid women before delivery, CMV IgG and IgM antibodies were measured by ELISA method and CMV-DNA detection by PCR in ~10% of their infants. 100% of women were immune to CMV infection (CMV-IgG positive) were detected in mothers and newborns. Therefore, we can not compare gestational age and weight of infants in seropositive and serongegative mothers. Probably, in Iranian pregnant women, CMV screening test is not recommended.http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/1086.pdf&manuscript_id=1086CytomegalovirusCongenital CMVCMV antibodyTORCH screening |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
"Siadati A Noorbakhsh S Ghazi F Rimaz Sh Monavari SHR |
spellingShingle |
"Siadati A Noorbakhsh S Ghazi F Rimaz Sh Monavari SHR Cytomegalovirus infection in primiparous pregnant women and their neonates Acta Medica Iranica Cytomegalovirus Congenital CMV CMV antibody TORCH screening |
author_facet |
"Siadati A Noorbakhsh S Ghazi F Rimaz Sh Monavari SHR |
author_sort |
"Siadati A |
title |
Cytomegalovirus infection in primiparous pregnant women and their neonates |
title_short |
Cytomegalovirus infection in primiparous pregnant women and their neonates |
title_full |
Cytomegalovirus infection in primiparous pregnant women and their neonates |
title_fullStr |
Cytomegalovirus infection in primiparous pregnant women and their neonates |
title_full_unstemmed |
Cytomegalovirus infection in primiparous pregnant women and their neonates |
title_sort |
cytomegalovirus infection in primiparous pregnant women and their neonates |
publisher |
Tehran University of Medical Sciences |
series |
Acta Medica Iranica |
issn |
0044-6025 |
publishDate |
2002-07-01 |
description |
Cytomegaloviurs (CMV) is the most frequent cause of congenital infection in humans. In various parts of the world the prevalence of antibodies to CMV ranges from 40-100%. The prevalence of primary infection with CMV in pregnant Iranian women and risk of congenital CMV infection in their neonates are unknown. To Determine the prevalence of CMV infection in primiparous pregnant (youner) women and incidence rate of cangenital CMV infection among preterm and full-term infants borned from these women, in serum of 164 primigravid women before delivery, CMV IgG and IgM antibodies were measured by ELISA method and CMV-DNA detection by PCR in ~10% of their infants. 100% of women were immune to CMV infection (CMV-IgG positive) were detected in mothers and newborns. Therefore, we can not compare gestational age and weight of infants in seropositive and serongegative mothers. Probably, in Iranian pregnant women, CMV screening test is not recommended. |
topic |
Cytomegalovirus Congenital CMV CMV antibody TORCH screening |
url |
http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/1086.pdf&manuscript_id=1086 |
work_keys_str_mv |
AT siadatia cytomegalovirusinfectioninprimiparouspregnantwomenandtheirneonates AT noorbakhshs cytomegalovirusinfectioninprimiparouspregnantwomenandtheirneonates AT ghazif cytomegalovirusinfectioninprimiparouspregnantwomenandtheirneonates AT rimazsh cytomegalovirusinfectioninprimiparouspregnantwomenandtheirneonates AT monavarishr cytomegalovirusinfectioninprimiparouspregnantwomenandtheirneonates |
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