Biological effects of cell-phone radiofrequency waves exposure on fertilization in mice; an in vivo and in vitro study
Increasing use of cell-phone is one of the most important risk factors for population health. We designed an experimental study aimed at evaluating the effects of cell-phone radiofrequency (RF) waves exposure on fertilization in mice. Two hundred male and female NMRI-mice were used. One hundred male...
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doaj-515e7a0825344e869b136c00e0a3a8652020-11-25T02:08:34ZengSpringerOpenMiddle East Fertility Society Journal1110-56902018-06-01232148153Biological effects of cell-phone radiofrequency waves exposure on fertilization in mice; an in vivo and in vitro studyDaryoush Fatehi0Maryam Anjomshoa1Mohsen Mohammadi2Mohammad Seify3Ayoob Rostamzadeh4Department of Medical Physics, Faculty of Medicine, Shahrekord University of Medical Sciences, Shahrekord, IranDepartment of Embryology and Histology, Faculty of Medicine, Shahrekord University of Medical Sciences, Shahrekord, IranDepartment of Pharmaceutical Biotechnology, Faculty of Pharmacy, Lorestan University of Medical Sciences, Khorramabad, IranDepartment of Anatomical Sciences, Faculty of Medicine, Tarbiat Modares University, Tehran, IranCellular and Molecular Research Center, Basic Health Sciences Institute, Department of Anatomy and Neuroscience, Faculty of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran; Corresponding author.Increasing use of cell-phone is one of the most important risk factors for population health. We designed an experimental study aimed at evaluating the effects of cell-phone radiofrequency (RF) waves exposure on fertilization in mice. Two hundred male and female NMRI-mice were used. One hundred males divided in five groups (n = 20) as control and exposed groups. Those irradiated with cell-phone RF in “Standby-mode” 1, 5 and 10 h daily named groups II, III and IV; respectively. Group V irradiated with cell-phone on “Active-mode” one hour daily. After 30 days irradiation, 50 males and 50 females were kept 24 h to assess their embryos. Fifty males were scarified to evaluate both in vitro and in vivo parameters, and 50 females received PMSG & HCG for both quantitative and qualitative evaluation. Comparing groups III, IV and V with control-group showed significantly decreased in the number of two-cell embryos (p = .000); however, a significant increase was found in the number of dead embryos (p = .000). Furthermore, 5 h daily irradiation significantly decreased grade-A embryos (p = .015); while, it significantly increased grade-B, C and D embryos (p-values = 0.026, 0.007, 0.006; respectively). Moreover, comparing groups IV and V to control-group, significant increase was found in pregnancy duration (p = .005, p = .009; respectively). However, in the mentioned groups a significant decrease was seen in number of newborn mice (p = .001, p = .004; respectively). In conclusion our findings showed that the cell-phone radiation can affect development of embryos as well as the number of newborn and pregnancy duration in NMRI-mouse, which might be a significant cause of reproductive failure. Keywords: Fertility, IVF, RF, Cell-phone, Embryohttp://www.sciencedirect.com/science/article/pii/S1110569017301875 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Daryoush Fatehi Maryam Anjomshoa Mohsen Mohammadi Mohammad Seify Ayoob Rostamzadeh |
spellingShingle |
Daryoush Fatehi Maryam Anjomshoa Mohsen Mohammadi Mohammad Seify Ayoob Rostamzadeh Biological effects of cell-phone radiofrequency waves exposure on fertilization in mice; an in vivo and in vitro study Middle East Fertility Society Journal |
author_facet |
Daryoush Fatehi Maryam Anjomshoa Mohsen Mohammadi Mohammad Seify Ayoob Rostamzadeh |
author_sort |
Daryoush Fatehi |
title |
Biological effects of cell-phone radiofrequency waves exposure on fertilization in mice; an in vivo and in vitro study |
title_short |
Biological effects of cell-phone radiofrequency waves exposure on fertilization in mice; an in vivo and in vitro study |
title_full |
Biological effects of cell-phone radiofrequency waves exposure on fertilization in mice; an in vivo and in vitro study |
title_fullStr |
Biological effects of cell-phone radiofrequency waves exposure on fertilization in mice; an in vivo and in vitro study |
title_full_unstemmed |
Biological effects of cell-phone radiofrequency waves exposure on fertilization in mice; an in vivo and in vitro study |
title_sort |
biological effects of cell-phone radiofrequency waves exposure on fertilization in mice; an in vivo and in vitro study |
publisher |
SpringerOpen |
series |
Middle East Fertility Society Journal |
issn |
1110-5690 |
publishDate |
2018-06-01 |
description |
Increasing use of cell-phone is one of the most important risk factors for population health. We designed an experimental study aimed at evaluating the effects of cell-phone radiofrequency (RF) waves exposure on fertilization in mice. Two hundred male and female NMRI-mice were used. One hundred males divided in five groups (n = 20) as control and exposed groups. Those irradiated with cell-phone RF in “Standby-mode” 1, 5 and 10 h daily named groups II, III and IV; respectively. Group V irradiated with cell-phone on “Active-mode” one hour daily. After 30 days irradiation, 50 males and 50 females were kept 24 h to assess their embryos. Fifty males were scarified to evaluate both in vitro and in vivo parameters, and 50 females received PMSG & HCG for both quantitative and qualitative evaluation. Comparing groups III, IV and V with control-group showed significantly decreased in the number of two-cell embryos (p = .000); however, a significant increase was found in the number of dead embryos (p = .000). Furthermore, 5 h daily irradiation significantly decreased grade-A embryos (p = .015); while, it significantly increased grade-B, C and D embryos (p-values = 0.026, 0.007, 0.006; respectively). Moreover, comparing groups IV and V to control-group, significant increase was found in pregnancy duration (p = .005, p = .009; respectively). However, in the mentioned groups a significant decrease was seen in number of newborn mice (p = .001, p = .004; respectively). In conclusion our findings showed that the cell-phone radiation can affect development of embryos as well as the number of newborn and pregnancy duration in NMRI-mouse, which might be a significant cause of reproductive failure. Keywords: Fertility, IVF, RF, Cell-phone, Embryo |
url |
http://www.sciencedirect.com/science/article/pii/S1110569017301875 |
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