17β-Estradiol responsiveness of MCF-7 laboratory strains is dependent on an autocrine signal activating the IGF type I receptor

<p>Abstract</p> <p>Background</p> <p>Human MCF-7 cells have been studied extensively as a model for breast cancer cell growth. Many reports have established that serum-starved MCF-7 cells can be induced to proliferate upon the sole addition of 17β-estradiol (E2). Howeve...

Full description

Bibliographic Details
Main Authors: Steenbergh Paul H, Sussenbach John S, van Schaik Richard FMA, Hamelers Irene HL
Format: Article
Language:English
Published: BMC 2003-07-01
Series:Cancer Cell International
Online Access:http://www.cancerci.com/content/3/1/10

Similar Items