17β-Estradiol responsiveness of MCF-7 laboratory strains is dependent on an autocrine signal activating the IGF type I receptor
<p>Abstract</p> <p>Background</p> <p>Human MCF-7 cells have been studied extensively as a model for breast cancer cell growth. Many reports have established that serum-starved MCF-7 cells can be induced to proliferate upon the sole addition of 17β-estradiol (E2). Howeve...
Main Authors: | Steenbergh Paul H, Sussenbach John S, van Schaik Richard FMA, Hamelers Irene HL |
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Format: | Article |
Language: | English |
Published: |
BMC
2003-07-01
|
Series: | Cancer Cell International |
Online Access: | http://www.cancerci.com/content/3/1/10 |
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