Multiple E3s promote the degradation of histone H3 variant Cse4
Abstract The histone H3-like protein Cse4/CENP-A acts as a key molecular marker that differentiates the special centromeric chromatin structures from bulk nucleosomes. As altered Cse4/CENP-A activity leads to genome instability, it is pivotal to understand the mechanism underlying Cse4 regulation. H...
Main Authors: | Haili Cheng, Xin Bao, Xin Gan, Shiwen Luo, Hai Rao |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-08-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-08923-w |
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