Candesartan inhibits inflammation through an angiotensin II type 1 receptor independent way in human embryonic kidney epithelial cells

Candesartan inhibits inflammation through an angiotensin II type 1 receptor independent way in human embryonic kidney epithelial cells

Abstract: Besides stimulating vasoconstriction, Angiotensin II is also well known in inducing reactive oxygen species and promoting inflammatory phenotype switch via its type 1 receptor. In clinic, Angiotensin II type 1 (AT1) receptor blocker like candesartan has been widely applied as an antihypert...

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Bibliographic Details
Main Authors: YING YU, HAIFENG JIANG, YANGYANG NIU, XIAOQIN ZHANG, YINGYING ZHANG, XI LIU, TAO QI, CHEN YU
Format: Article
Language:English
Published: Academia Brasileira de Ciências 2019-04-01
Series:Anais da Academia Brasileira de Ciências
Subjects:
Angiotensin II type 1 receptor blockers
candesartan
inflammation
reactive oxygen species
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000300701&lng=en&tlng=en

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