APC gene is modulated by hsa-miR-135b-5p in both diffuse and intestinal gastric cancer subtypes

APC gene is modulated by hsa-miR-135b-5p in both diffuse and intestinal gastric cancer subtypes

Abstract Background Several genetic and epigenetic alterations are related to the development and progression of Gastric Cancer (GC), one of those being the deregulated microRNA (miRNA) expression profile. miRNAs are small noncoding RNAs that negatively regulate the expression of thousands of genes,...

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Bibliographic Details
Main Authors: Leandro Magalhães, Luciana Gonçalves Quintana, Dielly Catrina Favacho Lopes, Amanda Ferreira Vidal, Adenilson Leão Pereira, Lara Carolina D’Araujo Pinto, João de Jesus Viana Pinheiro, André Salim Khayat, Luiz Ricardo Goulart, Rommel Burbano, Paulo Pimentel de Assumpção, Ândrea Ribeiro-dos-Santos
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Cancer
Subjects:
Gastric cancer
Hsa-miR-29c-5p
Hsa-miR-135b-5p
3D culture
DNMT3A
CDC42
Online Access:http://link.springer.com/article/10.1186/s12885-018-4980-7

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