The Potential of Chinese Herbal Medicines in the Treatment of Cervical Cancer
Cervical cancer is a global health issue and places a considerable economic and medical burden on society. Thus, a concerted effort to improve the treatment of cervical cancer is warranted. Although several treatment options are currently available for treating patients with cervical cancer, such as...
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doaj-51acbc4c7cda4aa39f7001a1d815d0ed2020-11-25T03:43:55ZengSAGE PublishingIntegrative Cancer Therapies1552-695X2019-07-011810.1177/1534735419861693The Potential of Chinese Herbal Medicines in the Treatment of Cervical CancerYi-Hsuan Hsiao MD, PhD0Chiao-Wen Lin PhD1Po-Hui Wang MD, PhD2Min-Chien Hsin PhD3Shun-Fa Yang PhD4Department of Obstetrics and Gynecology, Changhua Christian Hospital, ChanghuaDepartment of Dentistry, Chung Shan Medical University Hospital, TaichungDepartment of Obstetrics and Gynecology, Chung Shan Medical University Hospital, TaichungInstitute of Medicine, Chung Shan Medical University, TaichungDepartment of Medical Research, Chung Shan Medical University Hospital, TaichungCervical cancer is a global health issue and places a considerable economic and medical burden on society. Thus, a concerted effort to improve the treatment of cervical cancer is warranted. Although several treatment options are currently available for treating patients with cervical cancer, such as chemoradiation and neoadjuvant or adjuvant chemotherapy, more aggressive systemic therapies and newer therapeutic agents are under investigation. Medicinal herbs have long been used to treat diseases. In this review, we summarize studies analyzing the antitumor effects and underlying mechanisms of Chinese herbal medicines, including the effects of crude extracts and compounds in vitro or in animal models for inducing apoptosis and inhibiting invasion or metastasis. Chinese herbal medicines with therapeutic targeting, such as those that interfere with tumor growth and progression in cervical cancer, have been widely investigated. To apply Chinese herbal medicine in the treatment of cervical cancer, adequate clinical studies are required to confirm its clinical safety and efficiency. Further investigations focused on the purification, pharmacokinetics, and identification of compounds from Chinese herbal medicines in cervical cancer treatment are necessary to achieve the aforementioned treatment goals.https://doi.org/10.1177/1534735419861693 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Yi-Hsuan Hsiao MD, PhD Chiao-Wen Lin PhD Po-Hui Wang MD, PhD Min-Chien Hsin PhD Shun-Fa Yang PhD |
spellingShingle |
Yi-Hsuan Hsiao MD, PhD Chiao-Wen Lin PhD Po-Hui Wang MD, PhD Min-Chien Hsin PhD Shun-Fa Yang PhD The Potential of Chinese Herbal Medicines in the Treatment of Cervical Cancer Integrative Cancer Therapies |
author_facet |
Yi-Hsuan Hsiao MD, PhD Chiao-Wen Lin PhD Po-Hui Wang MD, PhD Min-Chien Hsin PhD Shun-Fa Yang PhD |
author_sort |
Yi-Hsuan Hsiao MD, PhD |
title |
The Potential of Chinese Herbal Medicines in the Treatment of Cervical Cancer |
title_short |
The Potential of Chinese Herbal Medicines in the Treatment of Cervical Cancer |
title_full |
The Potential of Chinese Herbal Medicines in the Treatment of Cervical Cancer |
title_fullStr |
The Potential of Chinese Herbal Medicines in the Treatment of Cervical Cancer |
title_full_unstemmed |
The Potential of Chinese Herbal Medicines in the Treatment of Cervical Cancer |
title_sort |
potential of chinese herbal medicines in the treatment of cervical cancer |
publisher |
SAGE Publishing |
series |
Integrative Cancer Therapies |
issn |
1552-695X |
publishDate |
2019-07-01 |
description |
Cervical cancer is a global health issue and places a considerable economic and medical burden on society. Thus, a concerted effort to improve the treatment of cervical cancer is warranted. Although several treatment options are currently available for treating patients with cervical cancer, such as chemoradiation and neoadjuvant or adjuvant chemotherapy, more aggressive systemic therapies and newer therapeutic agents are under investigation. Medicinal herbs have long been used to treat diseases. In this review, we summarize studies analyzing the antitumor effects and underlying mechanisms of Chinese herbal medicines, including the effects of crude extracts and compounds in vitro or in animal models for inducing apoptosis and inhibiting invasion or metastasis. Chinese herbal medicines with therapeutic targeting, such as those that interfere with tumor growth and progression in cervical cancer, have been widely investigated. To apply Chinese herbal medicine in the treatment of cervical cancer, adequate clinical studies are required to confirm its clinical safety and efficiency. Further investigations focused on the purification, pharmacokinetics, and identification of compounds from Chinese herbal medicines in cervical cancer treatment are necessary to achieve the aforementioned treatment goals. |
url |
https://doi.org/10.1177/1534735419861693 |
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