An R Package for Assessing Drug Synergism/Antagonism

An R Package for Assessing Drug Synergism/Antagonism

Synergistic and antagonistic drug interactions are important to consider when developing mixtures of anticancer or other types of drugs. Boik, Newman, and Boik (2008) proposed the MixLow method as an alternative to the Median-Effect method of Chou and Talalay (1984) for estimating drug interaction i...

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Bibliographic Details
Main Authors: John C. Boik, Balasubramanian Narasimhan
Format: Article
Language:English
Published: Foundation for Open Access Statistics 2010-10-01
Series:Journal of Statistical Software
Subjects:
synergism
antagonism
Loewe index
Mixlow method
cytotoxicity
R
Online Access:http://www.jstatsoft.org/v34/i06/paper

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