The investigation of the effect of (Mangifera indica) leaf extract on testis tissue and fertility in Wistar rats

• Main Authors: samaneh baghban, vahid Hemayatkhah Jahromi
• Format: Article
• Language: fas
• Published: Jahrom University of Medical Sciences 2015-04-01
• Series: فصلنامه دانشگاه علوم پزشکی جهرم
• Subjects: mango leaves; spermatogenesis; fertility; seminiferous tubules; rat
• Online Access: http://jmj.jums.ac.ir/article-1-463-en.html

Background: To use appropriate contraceptive methods, families planning have one of the important issues in global health. In medical systems, Medicinal properties have been attributed anti-diabetic, anti-oxidant, anti-fertility, etc. to various parts of mango tree. Materials and Methods: In this study, 35 male rats approximately 250 g was selected and were divided into: control, testator and experimental groups. The control group received sufficient water and food, 0.2 ml distilled water received to testator and about 500, 1000 and 1500 mg/ kg extract mango leaf was prescript to experimental group for 28 days. The weight of each mouse was measured and recorded in the first and last days. For evaluation of reproducibility, the samples were nearby with female rats. The samples were anesthetized and fixed for histological studies. Administration of extract mango leaf, significantly was decreased weight of body and testis at level of P≤ 0.05 . Results: The results showed that administration of extracted mango leaf, significantly decreased weight of body and testis. The number of male sexual cells, Sertoli and Ledig and the seminiferous tubule diameter, seminiferous epithelium height and fertility rate were decreased significantly. Conclusion: Extract mango leaf can be reduced effect on activity of the male reproductive system, and probably, can be recommended as a benefit material for birth control.