Food odors trigger Drosophila males to deposit a pheromone that guides aggregation and female oviposition decisions
Animals use olfactory cues for navigating complex environments. Food odors in particular provide crucial information regarding potential foraging sites. Many behaviors occur at food sites, yet how food odors regulate such behaviors at these sites is unclear. Using Drosophila melanogaster as an anima...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2015-09-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/08688 |
id |
doaj-520c8db9b0144e82860066847413a40e |
---|---|
record_format |
Article |
spelling |
doaj-520c8db9b0144e82860066847413a40e2021-05-05T00:02:43ZengeLife Sciences Publications LtdeLife2050-084X2015-09-01410.7554/eLife.08688Food odors trigger Drosophila males to deposit a pheromone that guides aggregation and female oviposition decisionsChun-Chieh Lin0Katharine A Prokop-Prigge1George Preti2Christopher J Potter3The Solomon H Snyder Department of Neuroscience, Center for Sensory Biology, Johns Hopkins University School of Medicine, Baltimore, United StatesMonell Chemical Senses Center, Philadelphia, United StatesMonell Chemical Senses Center, Philadelphia, United States; Department of Dermatology, School of Medicine, University of Pennsylvania, Philadelphia, United StatesThe Solomon H Snyder Department of Neuroscience, Center for Sensory Biology, Johns Hopkins University School of Medicine, Baltimore, United StatesAnimals use olfactory cues for navigating complex environments. Food odors in particular provide crucial information regarding potential foraging sites. Many behaviors occur at food sites, yet how food odors regulate such behaviors at these sites is unclear. Using Drosophila melanogaster as an animal model, we found that males deposit the pheromone 9-tricosene upon stimulation with the food-odor apple cider vinegar. This pheromone acts as a potent aggregation pheromone and as an oviposition guidance cue for females. We use genetic, molecular, electrophysiological, and behavioral approaches to show that 9-tricosene activates antennal basiconic Or7a receptors, a receptor activated by many alcohols and aldehydes such as the green leaf volatile E2-hexenal. We demonstrate that loss of Or7a positive neurons or the Or7a receptor abolishes aggregation behavior and oviposition site-selection towards 9-tricosene and E2-hexenal. 9-Tricosene thus functions via Or7a to link food-odor perception with aggregation and egg-laying decisions.https://elifesciences.org/articles/08688olfactionpheromoneovipositionaggregation |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Chun-Chieh Lin Katharine A Prokop-Prigge George Preti Christopher J Potter |
spellingShingle |
Chun-Chieh Lin Katharine A Prokop-Prigge George Preti Christopher J Potter Food odors trigger Drosophila males to deposit a pheromone that guides aggregation and female oviposition decisions eLife olfaction pheromone oviposition aggregation |
author_facet |
Chun-Chieh Lin Katharine A Prokop-Prigge George Preti Christopher J Potter |
author_sort |
Chun-Chieh Lin |
title |
Food odors trigger Drosophila males to deposit a pheromone that guides aggregation and female oviposition decisions |
title_short |
Food odors trigger Drosophila males to deposit a pheromone that guides aggregation and female oviposition decisions |
title_full |
Food odors trigger Drosophila males to deposit a pheromone that guides aggregation and female oviposition decisions |
title_fullStr |
Food odors trigger Drosophila males to deposit a pheromone that guides aggregation and female oviposition decisions |
title_full_unstemmed |
Food odors trigger Drosophila males to deposit a pheromone that guides aggregation and female oviposition decisions |
title_sort |
food odors trigger drosophila males to deposit a pheromone that guides aggregation and female oviposition decisions |
publisher |
eLife Sciences Publications Ltd |
series |
eLife |
issn |
2050-084X |
publishDate |
2015-09-01 |
description |
Animals use olfactory cues for navigating complex environments. Food odors in particular provide crucial information regarding potential foraging sites. Many behaviors occur at food sites, yet how food odors regulate such behaviors at these sites is unclear. Using Drosophila melanogaster as an animal model, we found that males deposit the pheromone 9-tricosene upon stimulation with the food-odor apple cider vinegar. This pheromone acts as a potent aggregation pheromone and as an oviposition guidance cue for females. We use genetic, molecular, electrophysiological, and behavioral approaches to show that 9-tricosene activates antennal basiconic Or7a receptors, a receptor activated by many alcohols and aldehydes such as the green leaf volatile E2-hexenal. We demonstrate that loss of Or7a positive neurons or the Or7a receptor abolishes aggregation behavior and oviposition site-selection towards 9-tricosene and E2-hexenal. 9-Tricosene thus functions via Or7a to link food-odor perception with aggregation and egg-laying decisions. |
topic |
olfaction pheromone oviposition aggregation |
url |
https://elifesciences.org/articles/08688 |
work_keys_str_mv |
AT chunchiehlin foododorstriggerdrosophilamalestodepositapheromonethatguidesaggregationandfemaleovipositiondecisions AT katharineaprokopprigge foododorstriggerdrosophilamalestodepositapheromonethatguidesaggregationandfemaleovipositiondecisions AT georgepreti foododorstriggerdrosophilamalestodepositapheromonethatguidesaggregationandfemaleovipositiondecisions AT christopherjpotter foododorstriggerdrosophilamalestodepositapheromonethatguidesaggregationandfemaleovipositiondecisions |
_version_ |
1721476604969877504 |