Salinomycin Promotes Anoikis and Decreases the CD44+/CD24- Stem-Like Population via Inhibition of STAT3 Activation in MDA-MB-231 Cells.
Triple-negative breast cancer (TNBC) is an aggressive tumor subtype with an enriched CD44+/CD24- stem-like population. Salinomycin is an antibiotic that has been shown to target cancer stem cells (CSC); however, the mechanisms of action involved have not been well characterized. The objective of the...
Main Authors: | Hyunsook An, Ji Young Kim, Eunhye Oh, Nahyun Lee, Youngkwan Cho, Jae Hong Seo |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4631341?pdf=render |
Similar Items
-
Goniothalamin Induces Necroptosis and Anoikis in Human Invasive Breast Cancer MDA-MB-231 Cells
by: Patompong Khaw-on, et al.
Published: (2019-08-01) -
Study on HPW-RX40-Induced Anoikis in Human Breast Cancer MDA-MB-231 Cells
by: Shin-Chu Shih, et al.
Published: (2011) -
Regulation of Cellular and Cancer Stem Cell-Related Putative Gene Expression of Parental and CD44<sup>+</sup>CD24<sup>−</sup> Sorted MDA-MB-231 Cells by Cisplatin
by: May Zie Koh, et al.
Published: (2021-04-01) -
Potential Effects of Chrysin on MDA-MB-231 Cells
by: Maimunah Ahmad, et al.
Published: (2010-03-01) -
Selective regain of <it>egfr </it>gene copies in CD44<sup>+</sup>/CD24<sup>-/low </sup>breast cancer cellular model MDA-MB-468
by: Andreas Antje, et al.
Published: (2010-03-01)