Immunoediting and Antigen Loss: Overcoming the Achilles Heel of Immunotherapy with Antigen Non-Specific Therapies

Immunoediting and Antigen Loss: Overcoming the Achilles Heel of Immunotherapy with Antigen Non-Specific Therapies

Cancer immunotherapy has emerged as a mainstream therapy option in the battle against cancer. Pre-clinical data demonstrates the ability of immunotherapy to harness the immune system to fight disseminated malignancy. Clinical translation has failed to recapitulate the promising results of pre-clin...

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Bibliographic Details
Main Authors: Arta Monir Monjazeb, Anthony E Zamora, Steven K Grossenbacher, Annie eMirsoian, Gail D Sckisel, William J Murphy
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-07-01
Series:Frontiers in Oncology
Subjects:
Immune Tolerance
Radiotherapy
cancer immunotherapy
immune suppression
immune surveillance
bystander T-cells
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00197/full

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