Leishmania infantum ecto-nucleoside triphosphate diphosphohydrolase-2 is an apyrase involved in macrophage infection and expressed in infected dogs.

Leishmania infantum ecto-nucleoside triphosphate diphosphohydrolase-2 is an apyrase involved in macrophage infection and expressed in infected dogs.

Visceral leishmaniasis is an important tropical disease, and Leishmania infantum chagasi (synonym of Leishmania infantum) is the main pathogenic agent of visceral leishmaniasis in the New World. Recently, ecto-nucleoside triphosphate diphosphohydrolases (E-NTPDases) were identified as enablers of in...

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Main Authors: Raphael De Souza Vasconcellos, Christiane Mariotini-Moura, Rodrigo Saar Gomes, Tiago Donatelli Serafim, Rafaela de Cássia Firmino, Matheus Silva E Bastos, Felipe Freitas de Castro, Claudia Miranda de Oliveira, Lucas Borges-Pereira, Anna Cláudia Alves de Souza, Ronny Francisco de Souza, Gabriel Andres Tafur Gómez, Aimara da Costa Pinheiro, Talles Eduardo Ferreira Maciel, Abelardo Silva-Júnior, Gustavo Costa Bressan, Márcia Rogéria Almeida, Munira Muhammad Abdel Baqui, Luís Carlos Crocco Afonso, Juliana Lopes Rangel Fietto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-11-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4230930?pdf=render

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