Protective effects of upregulated HO-1 gene against the apoptosis of human retinal pigment epithelial cells in vitro

Protective effects of upregulated HO-1 gene against the apoptosis of human retinal pigment epithelial cells in vitro

AIM: To investigate the protective effect of heme oxygenase-1 (HO-1) against H2O2-induced apoptosis in human ARPE-19 cells. METHODS: The lentiviral vector expressing HO-1 was prepared and transfected into apoptotic ARPE-19 cells induced by H2O2. Functional experiments including cell counting kit-8 (...

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Bibliographic Details
Main Authors: Yu Hong, Yu-Ping Liang, Wei-Qi Chen, Liu-Xia You, Qing-Feng Ni, Xiu-Yun Gao, Xiao-Rong Lin
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2021-05-01
Series:International Journal of Ophthalmology
Subjects:
retinitis pigmentosa
heme oxygenase-1
arpe-19 cell
mechanism
Online Access:http://ies.ijo.cn/en_publish/2021/5/20210503.pdf

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