Reduction and esterification of cholesterol and sitosterol by homogenates of feces
Mixtures of cholesterol-1,2-3H and sitosterol-4-14C have been incubated with suspensions of feces in order to compare the behavior of the phytosterol with transformations known to take place with cholesterol under these conditions. Within the limitations of the study, both labeled sterols were ester...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
1971-03-01
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| Series: | Journal of Lipid Research |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520395298 |
| Summary: | Mixtures of cholesterol-1,2-3H and sitosterol-4-14C have been incubated with suspensions of feces in order to compare the behavior of the phytosterol with transformations known to take place with cholesterol under these conditions. Within the limitations of the study, both labeled sterols were esterified to the same extent, and reduction of the Δ5 double bond to the saturated analogue proceeded equally in both substances. After correcting for procedural losses, the recoveries of 3H and 14C from the incubations were always less than the controls; this strongly indicates destruction of sterol by feces microorganisms. |
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| ISSN: | 0022-2275 |