A differential concentration-dependent effect of IVIg on neutrophil functions: relevance for anti-microbial and anti-inflammatory mechanisms.
BACKGROUND: Polymorphonuclear neutrophils (PMN) play a key role in host defences against invading microorganisms but can also potentiate detrimental inflammatory reactions in case of excessive or misdirected responses. Intravenous immunoglobulins (IVIg) are used to treat patients with immune deficie...
Main Authors: | Sarah Casulli, Selma Topçu, Lakhdar Fattoum, Stephan von Gunten, Hans-Uwe Simon, Jean-Luc Teillaud, Jagadeesh Bayry, Srini V Kaveri, Carole Elbim |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3204983?pdf=render |
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