Gut ghrelin regulates hepatic glucose production and insulin signaling via a gut-brain-liver pathway

Gut ghrelin regulates hepatic glucose production and insulin signaling via a gut-brain-liver pathway

Abstract Background Ghrelin modulates many physiological processes. However, the effects of intestinal ghrelin on hepatic glucose production (HGP) are still unclear. The current study was to explore the roles of intestinal ghrelin on glucose homeostasis and insulin signaling in the liver. Methods Th...

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Bibliographic Details
Main Authors: Yao Lin, Zerong Liang, Liping He, Mengliu Yang, Dongfang Liu, Harvest F. Gu, Hua Liu, Zhiming Zhu, Hongting Zheng, Ling Li, Gangyi Yang
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Cell Communication and Signaling
Subjects:
Insulin resistance
Glucose homeostasis
Duodenum
Ghrelin
Online Access:http://link.springer.com/article/10.1186/s12964-019-0321-y

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