Protein-polymer bioconjugates via a versatile oxygen tolerant photoinduced controlled radical polymerization approach

Amphiphilic protein-polymer conjugates remain largely unexplored due to synthetic protocols being complex. Here the authors explore an oxygen tolerant, photoinduced reversible-deactivated radical polymerization approach, which readily affords quantitative yields within 2 h and thus avoids damage to...

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Main Authors:	Alexis Theodorou, Evelina Liarou, David M. Haddleton, Iren Georgia Stavrakaki, Panagiotis Skordalidis, Richard Whitfield, Athina Anastasaki, Kelly Velonia
Format:	Article
Language:	English
Published:	Nature Publishing Group 2020-03-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-020-15259-z

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spelling	doaj-52a302da180e4272b67fd700c87a78a32021-05-11T08:53:15ZengNature Publishing GroupNature Communications2041-17232020-03-0111111110.1038/s41467-020-15259-zProtein-polymer bioconjugates via a versatile oxygen tolerant photoinduced controlled radical polymerization approachAlexis Theodorou0Evelina Liarou1David M. Haddleton2Iren Georgia Stavrakaki3Panagiotis Skordalidis4Richard Whitfield5Athina Anastasaki6Kelly Velonia7Department of Materials Science and Technology, University of CreteChemistry Department, University of WarwickChemistry Department, University of WarwickDepartment of Materials Science and Technology, University of CreteDepartment of Materials Science and Technology, University of CreteDepartment of Materials, ETH ZurichDepartment of Materials, ETH ZurichDepartment of Materials Science and Technology, University of CreteAmphiphilic protein-polymer conjugates remain largely unexplored due to synthetic protocols being complex. Here the authors explore an oxygen tolerant, photoinduced reversible-deactivated radical polymerization approach, which readily affords quantitative yields within 2 h and thus avoids damage to the secondary structure of the proteins.https://doi.org/10.1038/s41467-020-15259-z
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Alexis Theodorou Evelina Liarou David M. Haddleton Iren Georgia Stavrakaki Panagiotis Skordalidis Richard Whitfield Athina Anastasaki Kelly Velonia
spellingShingle	Alexis Theodorou Evelina Liarou David M. Haddleton Iren Georgia Stavrakaki Panagiotis Skordalidis Richard Whitfield Athina Anastasaki Kelly Velonia Protein-polymer bioconjugates via a versatile oxygen tolerant photoinduced controlled radical polymerization approach Nature Communications
author_facet	Alexis Theodorou Evelina Liarou David M. Haddleton Iren Georgia Stavrakaki Panagiotis Skordalidis Richard Whitfield Athina Anastasaki Kelly Velonia
author_sort	Alexis Theodorou
title	Protein-polymer bioconjugates via a versatile oxygen tolerant photoinduced controlled radical polymerization approach
title_short	Protein-polymer bioconjugates via a versatile oxygen tolerant photoinduced controlled radical polymerization approach
title_full	Protein-polymer bioconjugates via a versatile oxygen tolerant photoinduced controlled radical polymerization approach
title_fullStr	Protein-polymer bioconjugates via a versatile oxygen tolerant photoinduced controlled radical polymerization approach
title_full_unstemmed	Protein-polymer bioconjugates via a versatile oxygen tolerant photoinduced controlled radical polymerization approach
title_sort	protein-polymer bioconjugates via a versatile oxygen tolerant photoinduced controlled radical polymerization approach
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2020-03-01
description	Amphiphilic protein-polymer conjugates remain largely unexplored due to synthetic protocols being complex. Here the authors explore an oxygen tolerant, photoinduced reversible-deactivated radical polymerization approach, which readily affords quantitative yields within 2 h and thus avoids damage to the secondary structure of the proteins.
url	https://doi.org/10.1038/s41467-020-15259-z
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Protein-polymer bioconjugates via a versatile oxygen tolerant photoinduced controlled radical polymerization approach

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