Protein-polymer bioconjugates via a versatile oxygen tolerant photoinduced controlled radical polymerization approach
Amphiphilic protein-polymer conjugates remain largely unexplored due to synthetic protocols being complex. Here the authors explore an oxygen tolerant, photoinduced reversible-deactivated radical polymerization approach, which readily affords quantitative yields within 2 h and thus avoids damage to...
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Nature Publishing Group
2020-03-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-15259-z |
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doaj-52a302da180e4272b67fd700c87a78a32021-05-11T08:53:15ZengNature Publishing GroupNature Communications2041-17232020-03-0111111110.1038/s41467-020-15259-zProtein-polymer bioconjugates via a versatile oxygen tolerant photoinduced controlled radical polymerization approachAlexis Theodorou0Evelina Liarou1David M. Haddleton2Iren Georgia Stavrakaki3Panagiotis Skordalidis4Richard Whitfield5Athina Anastasaki6Kelly Velonia7Department of Materials Science and Technology, University of CreteChemistry Department, University of WarwickChemistry Department, University of WarwickDepartment of Materials Science and Technology, University of CreteDepartment of Materials Science and Technology, University of CreteDepartment of Materials, ETH ZurichDepartment of Materials, ETH ZurichDepartment of Materials Science and Technology, University of CreteAmphiphilic protein-polymer conjugates remain largely unexplored due to synthetic protocols being complex. Here the authors explore an oxygen tolerant, photoinduced reversible-deactivated radical polymerization approach, which readily affords quantitative yields within 2 h and thus avoids damage to the secondary structure of the proteins.https://doi.org/10.1038/s41467-020-15259-z |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Alexis Theodorou Evelina Liarou David M. Haddleton Iren Georgia Stavrakaki Panagiotis Skordalidis Richard Whitfield Athina Anastasaki Kelly Velonia |
spellingShingle |
Alexis Theodorou Evelina Liarou David M. Haddleton Iren Georgia Stavrakaki Panagiotis Skordalidis Richard Whitfield Athina Anastasaki Kelly Velonia Protein-polymer bioconjugates via a versatile oxygen tolerant photoinduced controlled radical polymerization approach Nature Communications |
author_facet |
Alexis Theodorou Evelina Liarou David M. Haddleton Iren Georgia Stavrakaki Panagiotis Skordalidis Richard Whitfield Athina Anastasaki Kelly Velonia |
author_sort |
Alexis Theodorou |
title |
Protein-polymer bioconjugates via a versatile oxygen tolerant photoinduced controlled radical polymerization approach |
title_short |
Protein-polymer bioconjugates via a versatile oxygen tolerant photoinduced controlled radical polymerization approach |
title_full |
Protein-polymer bioconjugates via a versatile oxygen tolerant photoinduced controlled radical polymerization approach |
title_fullStr |
Protein-polymer bioconjugates via a versatile oxygen tolerant photoinduced controlled radical polymerization approach |
title_full_unstemmed |
Protein-polymer bioconjugates via a versatile oxygen tolerant photoinduced controlled radical polymerization approach |
title_sort |
protein-polymer bioconjugates via a versatile oxygen tolerant photoinduced controlled radical polymerization approach |
publisher |
Nature Publishing Group |
series |
Nature Communications |
issn |
2041-1723 |
publishDate |
2020-03-01 |
description |
Amphiphilic protein-polymer conjugates remain largely unexplored due to synthetic protocols being complex. Here the authors explore an oxygen tolerant, photoinduced reversible-deactivated radical polymerization approach, which readily affords quantitative yields within 2 h and thus avoids damage to the secondary structure of the proteins. |
url |
https://doi.org/10.1038/s41467-020-15259-z |
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