Single Molecule Study of Hydrogen Bond Interactions Between Single Oligonucleotide and Aerolysin Sensing Interface

Single Molecule Study of Hydrogen Bond Interactions Between Single Oligonucleotide and Aerolysin Sensing Interface

The aerolysin nanopore displays a charming sensing capability for single oligonucleotide discrimination. When reading from the electrochemical signal, stronger interaction between the aerolysin nanopore and oligonucleotide represent prolonged duration time, thereby amplifying the hidden but intrinsi...

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Bibliographic Details
Main Authors: Meng-Yin Li, Ya-Qian Wang, Yao Lu, Yi-Lun Ying, Yi-Tao Long
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Chemistry
Subjects:
single-molecule interface
oligonucleotide
nanopore
hydrogen bond
nanoconfinement
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2019.00528/full

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