Genomic locus modulating corneal thickness in the mouse identifies POU6F2 as a potential risk of developing glaucoma.

Genomic locus modulating corneal thickness in the mouse identifies POU6F2 as a potential risk of developing glaucoma.

Central corneal thickness (CCT) is one of the most heritable ocular traits and it is also a phenotypic risk factor for primary open angle glaucoma (POAG). The present study uses the BXD Recombinant Inbred (RI) strains to identify novel quantitative trait loci (QTLs) modulating CCT in the mouse with...

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Bibliographic Details
Main Authors: Rebecca King, Felix L Struebing, Ying Li, Jiaxing Wang, Allison Ashley Koch, Jessica N Cooke Bailey, Puya Gharahkhani, International Glaucoma Genetics Consortium, NEIGHBORHOOD Consortium, Stuart MacGregor, R Rand Allingham, Michael A Hauser, Janey L Wiggs, Eldon E Geisert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1007145

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