Preparation of Amphiphilic Chitosan–Graphene Oxide–Cellulose Nanocrystalline Composite Hydrogels and Their Biocompatibility and Antibacterial Properties
Environmental-friendly nanocomposite hydrogels of carboxymethyl-hexanoyl chitosan (CHC), graphene oxide (GO) and cellulose nanocrystals (CNCs) were combined to produce a bio-hydrogel with great biocompatibility and antibacterial ability. The size of the GO nanosheets was about 200−500 nm,...
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2019-07-01
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| Series: | Applied Sciences |
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| Online Access: | https://www.mdpi.com/2076-3417/9/15/3051 |
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doaj-52f2c3f1704a44e69da26edeffbaf7332020-11-25T02:16:41ZengMDPI AGApplied Sciences2076-34172019-07-01915305110.3390/app9153051app9153051Preparation of Amphiphilic Chitosan–Graphene Oxide–Cellulose Nanocrystalline Composite Hydrogels and Their Biocompatibility and Antibacterial PropertiesMing-Chien Yang0Yi-Qun Tseng1Kun-Ho Liu2Yu-Wei Cheng3Wan-Tzu Chen4Wei-Ting Chen5Chia-Wei Hsiao6Ming-Chi Yung7Chuan-Chih Hsu8Ting-Yu Liu9Department of Materials Science and Engineering, National Taiwan University of Science and Technology, Taipei 10607, TaiwanDepartment of Materials Science and Engineering, National Taiwan University of Science and Technology, Taipei 10607, TaiwanAdvanced Delivery Biotechnology Co., Ltd., Hsinchu 30325, TaiwanDepartment of Materials Engineering, Ming Chi University of Technology, New Taipei City 24301, TaiwanDepartment of Materials Science and Engineering, National Taiwan University of Science and Technology, Taipei 10607, TaiwanDepartment of Materials Engineering, Ming Chi University of Technology, New Taipei City 24301, TaiwanDepartment of Materials Engineering, Ming Chi University of Technology, New Taipei City 24301, TaiwanDivision of Cardiovascular Surgery, Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University Hospital, Taipei 11031, TaiwanDivision of Cardiovascular Surgery, Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University Hospital, Taipei 11031, TaiwanDepartment of Materials Engineering, Ming Chi University of Technology, New Taipei City 24301, TaiwanEnvironmental-friendly nanocomposite hydrogels of carboxymethyl-hexanoyl chitosan (CHC), graphene oxide (GO) and cellulose nanocrystals (CNCs) were combined to produce a bio-hydrogel with great biocompatibility and antibacterial ability. The size of the GO nanosheets was about 200−500 nm, and the CNCs had a length of 100−200 nm and a width of 10−20 nm, as shown by transmission electron microscopy (TEM). X-ray photoelectron spectroscopy (XPS) was utilized for the analysis of the oxygen functional groups of GO. The homogeneous dispersion of the CHC/GO/CNC nanocomposite hydrogel showed significantly higher water absorption capacity and water retention capability. In addition, inhibition of a variety of microorganisms (gram-negative and gram-positive bacteria and fungi) by the introduction of the CHC/GO/CNC nanocomposite hydrogel demonstrated that there is a great opportunity to use it in the bio-medical field, such as for plastic masks and wound dressings.https://www.mdpi.com/2076-3417/9/15/3051amphiphatic chitosancellulose nanocrystalsgraphene oxidenanocomposite hydrogelantibacterial ability |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Ming-Chien Yang Yi-Qun Tseng Kun-Ho Liu Yu-Wei Cheng Wan-Tzu Chen Wei-Ting Chen Chia-Wei Hsiao Ming-Chi Yung Chuan-Chih Hsu Ting-Yu Liu |
| spellingShingle |
Ming-Chien Yang Yi-Qun Tseng Kun-Ho Liu Yu-Wei Cheng Wan-Tzu Chen Wei-Ting Chen Chia-Wei Hsiao Ming-Chi Yung Chuan-Chih Hsu Ting-Yu Liu Preparation of Amphiphilic Chitosan–Graphene Oxide–Cellulose Nanocrystalline Composite Hydrogels and Their Biocompatibility and Antibacterial Properties Applied Sciences amphiphatic chitosan cellulose nanocrystals graphene oxide nanocomposite hydrogel antibacterial ability |
| author_facet |
Ming-Chien Yang Yi-Qun Tseng Kun-Ho Liu Yu-Wei Cheng Wan-Tzu Chen Wei-Ting Chen Chia-Wei Hsiao Ming-Chi Yung Chuan-Chih Hsu Ting-Yu Liu |
| author_sort |
Ming-Chien Yang |
| title |
Preparation of Amphiphilic Chitosan–Graphene Oxide–Cellulose Nanocrystalline Composite Hydrogels and Their Biocompatibility and Antibacterial Properties |
| title_short |
Preparation of Amphiphilic Chitosan–Graphene Oxide–Cellulose Nanocrystalline Composite Hydrogels and Their Biocompatibility and Antibacterial Properties |
| title_full |
Preparation of Amphiphilic Chitosan–Graphene Oxide–Cellulose Nanocrystalline Composite Hydrogels and Their Biocompatibility and Antibacterial Properties |
| title_fullStr |
Preparation of Amphiphilic Chitosan–Graphene Oxide–Cellulose Nanocrystalline Composite Hydrogels and Their Biocompatibility and Antibacterial Properties |
| title_full_unstemmed |
Preparation of Amphiphilic Chitosan–Graphene Oxide–Cellulose Nanocrystalline Composite Hydrogels and Their Biocompatibility and Antibacterial Properties |
| title_sort |
preparation of amphiphilic chitosan–graphene oxide–cellulose nanocrystalline composite hydrogels and their biocompatibility and antibacterial properties |
| publisher |
MDPI AG |
| series |
Applied Sciences |
| issn |
2076-3417 |
| publishDate |
2019-07-01 |
| description |
Environmental-friendly nanocomposite hydrogels of carboxymethyl-hexanoyl chitosan (CHC), graphene oxide (GO) and cellulose nanocrystals (CNCs) were combined to produce a bio-hydrogel with great biocompatibility and antibacterial ability. The size of the GO nanosheets was about 200−500 nm, and the CNCs had a length of 100−200 nm and a width of 10−20 nm, as shown by transmission electron microscopy (TEM). X-ray photoelectron spectroscopy (XPS) was utilized for the analysis of the oxygen functional groups of GO. The homogeneous dispersion of the CHC/GO/CNC nanocomposite hydrogel showed significantly higher water absorption capacity and water retention capability. In addition, inhibition of a variety of microorganisms (gram-negative and gram-positive bacteria and fungi) by the introduction of the CHC/GO/CNC nanocomposite hydrogel demonstrated that there is a great opportunity to use it in the bio-medical field, such as for plastic masks and wound dressings. |
| topic |
amphiphatic chitosan cellulose nanocrystals graphene oxide nanocomposite hydrogel antibacterial ability |
| url |
https://www.mdpi.com/2076-3417/9/15/3051 |
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