Molecular Alterations Associated with Osteosarcoma Development

Osteosarcoma is the most frequent malignant primary bone tumor characterized by a high potency to form lung metastases which is the main cause of death. Unfortunately, the conventional chemotherapy is not fully effective on osteosarcoma metastases. The progression of a primary tumor to metastasis re...

Full description

Bibliographic Details
Main Authors: Kosei Ando, Kanji Mori, Franck Verrecchia, Baud’huin Marc, Françoise Rédini, Dominique Heymann
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Sarcoma
Online Access:http://dx.doi.org/10.1155/2012/523432