Mentha suaveolens Ehrh. (Lamiaceae) Essential Oil and Its Main Constituent Piperitenone Oxide: Biological Activities and Chemistry
Since herbal medicines play an important role in the treatment of a wide range of diseases, there is a growing need for their quality control and standardization. Mentha suaveolens Ehrh. (MS) is an aromatic herb with fruit and a spearmint flavor, used in the Mediterranean areas as a traditional med...
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doaj-5323f70a73d1466baef98b9d9c8f83cd2020-11-24T23:38:46ZengMDPI AGMolecules1420-30492015-05-012058605863310.3390/molecules20058605molecules20058605Mentha suaveolens Ehrh. (Lamiaceae) Essential Oil and Its Main Constituent Piperitenone Oxide: Biological Activities and ChemistryMijat Božović0Adele Pirolli1Rino Ragno2Rome Center for Molecular Design, Department of Drug Chemistry and Technology, Sapienza University, P.le Aldo Moro 5, 00185 Rome, ItalyRome Center for Molecular Design, Department of Drug Chemistry and Technology, Sapienza University, P.le Aldo Moro 5, 00185 Rome, ItalyRome Center for Molecular Design, Department of Drug Chemistry and Technology, Sapienza University, P.le Aldo Moro 5, 00185 Rome, ItalySince herbal medicines play an important role in the treatment of a wide range of diseases, there is a growing need for their quality control and standardization. Mentha suaveolens Ehrh. (MS) is an aromatic herb with fruit and a spearmint flavor, used in the Mediterranean areas as a traditional medicine. It has an extensive range of biological activities, including cytotoxic, antimicrobial, antioxidant, anti-inflammatory, hypotensive and insecticidal properties, among others. This study aims to review the scientific findings and research reported to date on MS that prove many of the remarkable various biological actions, effects and some uses of this species as a source of bioactive natural compounds. On the other hand, piperitenone oxide (PO), the major chemical constituent of the carvone pathway MS essential oil, has been reported to exhibit numerous bioactivities in cells and animals. Thus, this integrated overview also surveys and interprets the present knowledge of chemistry and analysis of this oxygenated monoterpene, as well as its beneficial bioactivities. Areas for future research are suggested.http://www.mdpi.com/1420-3049/20/5/8605Mentha suaveolens Ehrh.essential oilextractspiperitenone oxidebiological activity |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mijat Božović Adele Pirolli Rino Ragno |
spellingShingle |
Mijat Božović Adele Pirolli Rino Ragno Mentha suaveolens Ehrh. (Lamiaceae) Essential Oil and Its Main Constituent Piperitenone Oxide: Biological Activities and Chemistry Molecules Mentha suaveolens Ehrh. essential oil extracts piperitenone oxide biological activity |
author_facet |
Mijat Božović Adele Pirolli Rino Ragno |
author_sort |
Mijat Božović |
title |
Mentha suaveolens Ehrh. (Lamiaceae) Essential Oil and Its Main Constituent Piperitenone Oxide: Biological Activities and Chemistry |
title_short |
Mentha suaveolens Ehrh. (Lamiaceae) Essential Oil and Its Main Constituent Piperitenone Oxide: Biological Activities and Chemistry |
title_full |
Mentha suaveolens Ehrh. (Lamiaceae) Essential Oil and Its Main Constituent Piperitenone Oxide: Biological Activities and Chemistry |
title_fullStr |
Mentha suaveolens Ehrh. (Lamiaceae) Essential Oil and Its Main Constituent Piperitenone Oxide: Biological Activities and Chemistry |
title_full_unstemmed |
Mentha suaveolens Ehrh. (Lamiaceae) Essential Oil and Its Main Constituent Piperitenone Oxide: Biological Activities and Chemistry |
title_sort |
mentha suaveolens ehrh. (lamiaceae) essential oil and its main constituent piperitenone oxide: biological activities and chemistry |
publisher |
MDPI AG |
series |
Molecules |
issn |
1420-3049 |
publishDate |
2015-05-01 |
description |
Since herbal medicines play an important role in the treatment of a wide range of diseases, there is a growing need for their quality control and standardization. Mentha suaveolens Ehrh. (MS) is an aromatic herb with fruit and a spearmint flavor, used in the Mediterranean areas as a traditional medicine. It has an extensive range of biological activities, including cytotoxic, antimicrobial, antioxidant, anti-inflammatory, hypotensive and insecticidal properties, among others. This study aims to review the scientific findings and research reported to date on MS that prove many of the remarkable various biological actions, effects and some uses of this species as a source of bioactive natural compounds. On the other hand, piperitenone oxide (PO), the major chemical constituent of the carvone pathway MS essential oil, has been reported to exhibit numerous bioactivities in cells and animals. Thus, this integrated overview also surveys and interprets the present knowledge of chemistry and analysis of this oxygenated monoterpene, as well as its beneficial bioactivities. Areas for future research are suggested. |
topic |
Mentha suaveolens Ehrh. essential oil extracts piperitenone oxide biological activity |
url |
http://www.mdpi.com/1420-3049/20/5/8605 |
work_keys_str_mv |
AT mijatbozovic menthasuaveolensehrhlamiaceaeessentialoilanditsmainconstituentpiperitenoneoxidebiologicalactivitiesandchemistry AT adelepirolli menthasuaveolensehrhlamiaceaeessentialoilanditsmainconstituentpiperitenoneoxidebiologicalactivitiesandchemistry AT rinoragno menthasuaveolensehrhlamiaceaeessentialoilanditsmainconstituentpiperitenoneoxidebiologicalactivitiesandchemistry |
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