Paraganglioma of the Urinary Bladder – A Diagnostic Dilemma

• Main Authors: Bhaskar Smitha, Koppalkar Kiran Rachana, Pai Muktha Ramesh
• Format: Article
• Language: English
• Published: JCDR Research and Publications Private Limited 2018-11-01
• Series: Journal of Clinical and Diagnostic Research
• Subjects: catecholamines; chromogranin; cystectomy; neuroendocrine tumour; transurethral resection
• Online Access: https://jcdr.net/articles/PDF/12243/37738_CE[Ra]_F(P)_PF1(A_SHU)_PFA(A_SHU)_PN(SHU).pdf

Paraganglioma of the urinary bladder is a unique neuroendocrine tumour originating from chromaffin tissue of the sympathetic nervous system. Clinically, patients may be asymptomatic or may present with hypertension or haematuria. Imaging features may suggest urothelial carcinoma. An uncommon case of a silent paraganglioma of the urinary bladder in an elderly female is documented here, who presented with a single episode of haematuria. Transurethral resection biopsy was performed with suspicion of malignancy. Histopathological evaluation revealed paraganglioma of the urinary bladder, which was confirmed by immunohistochemistry. These tumours require complete surgical excision and should be included in the differential diagnosis of any solitary bladder mass.