Tfh1 Cells in Germinal Centers During Chronic HIV/SIV Infection

Tfh1 Cells in Germinal Centers During Chronic HIV/SIV Infection

T follicular helper CD4 cells (Tfh) are essential for the development and maintenance of germinal center (GC) reactions, a critical process that promotes the generation of long-lived high affinity humoral immunity. It is becoming increasingly evident that GC-Tfh cells are heterogeneous in nature wit...

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Bibliographic Details
Main Authors: Vijayakumar Velu, Geetha Mylvaganam, Chris Ibegbu, Rama Rao Amara
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Immunology
Subjects:
Tfh1 cells
germinal centers
HIV/SIV reservoirs
follicular CD8 T cells
Tfh cells
HIV/SIV infection
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01272/full

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