Identification of Jak-STAT signaling involvement in sarcoidosis severity via a novel microRNA-regulated peripheral blood mononuclear cell gene signature
Abstract Sarcoidosis is a granulomatous lung disorder of unknown cause. The majority of individuals with sarcoidosis spontaneously achieve full remission (uncomplicated sarcoidosis), however, ~20% of sarcoidosis-affected individuals experience progressive lung disease or cardiac and nervous system i...
Main Authors: | Tong Zhou, Nancy Casanova, Nima Pouladi, Ting Wang, Yves Lussier, Kenneth S. Knox, Joe G. N. Garcia |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-06-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-04109-6 |
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