Anlotinib as a promising inhibitor on tumor growth of oral squamous cell carcinoma through cell apoptosis and mitotic catastrophe

Anlotinib as a promising inhibitor on tumor growth of oral squamous cell carcinoma through cell apoptosis and mitotic catastrophe

Abstract Background Oral squamous cell carcinoma (OSCC) has been one of the most malignant cancers in head and neck region. Anlotinib is a tyrosine kinase inhibitor targeting several receptors such as vascular endothelial growth factor receptor (VEGFR), fibroblast growth factor receptor (FGFR), plat...

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Bibliographic Details
Main Authors: Zhaoming Deng, Wei Liao, Wei Wei, Guihua Zhong, Chao He, Hongbo Zhang, Qiaodan Liu, Xiwei Xu, Jun Liang, Zhigang Liu
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Cancer Cell International
Subjects:
Oral squamous cell carcinoma
Anlotinib
VEGFR-2
Cell Apoptosis
Cell cycle arrest
Mitotic catastrophe
Online Access:https://doi.org/10.1186/s12935-020-01721-x

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