Medicarpin, a Natural Pterocarpan, Heals Cortical Bone Defect by Activation of Notch and Wnt Canonical Signaling Pathways.

Medicarpin, a Natural Pterocarpan, Heals Cortical Bone Defect by Activation of Notch and Wnt Canonical Signaling Pathways.

We evaluated the bone regeneration and healing effect of Medicarpin (med) in cortical bone defect model that heals by intramembranous ossification. For the study, female Sprague-Dawley rats were ovariectomized and rendered osteopenic. A drill hole injury was generated in mid femoral bones of all the...

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Main Authors: Manisha Dixit, Ashutosh Raghuvanshi, Chandra Prakash Gupta, Jyoti Kureel, Mohd Nizam Mansoori, Priyanka Shukla, Aijaz A John, Kavita Singh, Dipak Purohit, Pallavi Awasthi, Divya Singh, Atul Goel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4676632?pdf=render

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http://europepmc.org/articles/PMC4676632?pdf=render

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