Myosin 1F Regulates M1-Polarization by Stimulating Intercellular Adhesion in Macrophages

Myosin 1F Regulates M1-Polarization by Stimulating Intercellular Adhesion in Macrophages

Intestinal macrophages are highly mobile cells with extraordinary plasticity and actively contribute to cytokine-mediated epithelial cell damage. The mechanisms triggering macrophage polarization into a proinflammatory phenotype are unknown. Here, we report that during inflammation macrophages enhan...

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Bibliographic Details
Main Authors: Zayda L. Piedra-Quintero, Carolina Serrano, Nicolás Villegas-Sepúlveda, José L. Maravillas-Montero, Sandra Romero-Ramírez, Mineko Shibayama, Oscar Medina-Contreras, Porfirio Nava, Leopoldo Santos-Argumedo
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Immunology
Subjects:
myosin 1F
intercellular adhesion
M1-polarization
inflammation
Akt/mTOR/STAT signaling
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.03118/full

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