Neurological manifestations of COVID-19: A brief review

• Main Authors: Kirti Sachdev, Sumita Agrawal, Pranav Ish, Nitesh Gupta, Kapil Raheja
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2020-01-01
• Series: Indian Journal of Medical Research
• Subjects: covid-19 - csf - encephalopathy - intracranial pressure - ischaemic stroke - nervous system diseases - neuronal cells - sars-cov-2 - venous thromboembolism
• Online Access: http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2020;volume=152;issue=1;spage=41;epage=47;aulast=Sachdev

The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been predominantly a respiratory manifestation. Currently, with evolving literature, neurological signs are being increasingly recognized. Studies have reported that SARS-CoV-2 affects all aspects of the nervous system including the central nervous system (CNS), peripheral nervous system (PNS) and the muscular system as well. Not all patients have reverse transcription-polymerase chain reaction positive for the virus in the cerebrospinal fluid, and diagnosing the association of the virus with the myriad of neurological manifestations can be a challenge. It is important that clinicians have a high-index of suspicion for COVID-19 in patients presenting with new-onset neurological symptoms. This will lead to early diagnosis and specific management. Further studies are desired to unravel the varied neurological manifestations, treatment, outcome and long-term sequel in COVID-19 patients.