Retinopathy of prematurity: Revisiting incidence and risk factors from Oman compared to other countries
Purpose: The purpose of this study is to determine the incidence of retinopathy of prematurity (ROP) and the maternal/neonatal risk factors at a tertiary care hospital in Oman, compared to other countries. Patients and Methods: A retrospective analysis of premature neonates born with gestational age...
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doaj-53a85faff9334d32918dece9e2f4be2a2020-11-24T23:02:14ZengWolters Kluwer Medknow PublicationsOman Journal of Ophthalmology0974-620X2017-01-01101263210.4103/ojo.OJO_234_2014Retinopathy of prematurity: Revisiting incidence and risk factors from Oman compared to other countriesZenaida Soriano ReyesSharef Waadallah Al-MulaabedFlordeliz BataclanCheryl MontemayorAnuradha GaneshSanaa Al-ZuhaibiHuda Al-WailiFatma Al-WahibiPurpose: The purpose of this study is to determine the incidence of retinopathy of prematurity (ROP) and the maternal/neonatal risk factors at a tertiary care hospital in Oman, compared to other countries. Patients and Methods: A retrospective analysis of premature neonates born with gestational age (GA) 24–32 weeks at Sultan Qaboos University Hospital, Oman, from January 2007 to December 2010. Maternal and neonatal in-hospital course was retrieved. The incidence of ROP was reported. Risk factors analyses were performed using univariate and multivariate statistics. Results: A total of 171 neonates (57% males, 43% females) were included for analysis. The incidence of ROP (any stage) was 69/171 (40.4%). Infants with ROP had significantly lower GA (27.7±2 weeks) compared to non-ROP group (30.2±1.7 weeks), P < 0.001),P < 0.001) and significantly lower birth weight (BW) (948 ± 242 g in ROP group vs. 1348 ± 283 g in non-ROP group;P < 0.001). Other significant risk factors associated with ROP were: small for GA, respiratory distress syndrome, requirement for ventilation, duration of ventilation or oxygen therapy, bronchopulmonary dysplasia, hyperglycemia, late onset sepsis (clinical or proven), necrotizing enterocolitis, patent ductus arteriosus, seizures, and number of blood transfusions. There was no significant difference in maternal characteristics between the ROP and non-ROP groups except that mothers of infants with ROP were found to be significantly younger. Logistic regression analysis revealed early GA, low BW, duration of Oxygen therapy, and late-onset clinical or proven sepsis as independent risk factors. Conclusion: ROP is still commonly encountered in neonatal practice in Oman and other countries. Early GA, low BW, and prolonged oxygen therapy continue to be the main risk factors associated with the occurrence of ROP in our setting. In addition, an important preventable risk factor identified in our cohort includes clinical or proven late-onset sepsis.http://www.ojoonline.org/article.asp?issn=0974-620X;year=2017;volume=10;issue=1;spage=26;epage=32;aulast=ReyesIncidenceneonatesOmanprematureretinopathy of prematurityrisk factors |
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DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Zenaida Soriano Reyes Sharef Waadallah Al-Mulaabed Flordeliz Bataclan Cheryl Montemayor Anuradha Ganesh Sanaa Al-Zuhaibi Huda Al-Waili Fatma Al-Wahibi |
spellingShingle |
Zenaida Soriano Reyes Sharef Waadallah Al-Mulaabed Flordeliz Bataclan Cheryl Montemayor Anuradha Ganesh Sanaa Al-Zuhaibi Huda Al-Waili Fatma Al-Wahibi Retinopathy of prematurity: Revisiting incidence and risk factors from Oman compared to other countries Oman Journal of Ophthalmology Incidence neonates Oman premature retinopathy of prematurity risk factors |
author_facet |
Zenaida Soriano Reyes Sharef Waadallah Al-Mulaabed Flordeliz Bataclan Cheryl Montemayor Anuradha Ganesh Sanaa Al-Zuhaibi Huda Al-Waili Fatma Al-Wahibi |
author_sort |
Zenaida Soriano Reyes |
title |
Retinopathy of prematurity: Revisiting incidence and risk factors from Oman compared to other countries |
title_short |
Retinopathy of prematurity: Revisiting incidence and risk factors from Oman compared to other countries |
title_full |
Retinopathy of prematurity: Revisiting incidence and risk factors from Oman compared to other countries |
title_fullStr |
Retinopathy of prematurity: Revisiting incidence and risk factors from Oman compared to other countries |
title_full_unstemmed |
Retinopathy of prematurity: Revisiting incidence and risk factors from Oman compared to other countries |
title_sort |
retinopathy of prematurity: revisiting incidence and risk factors from oman compared to other countries |
publisher |
Wolters Kluwer Medknow Publications |
series |
Oman Journal of Ophthalmology |
issn |
0974-620X |
publishDate |
2017-01-01 |
description |
Purpose: The purpose of this study is to determine the incidence of retinopathy of prematurity (ROP) and the maternal/neonatal risk factors at a tertiary care hospital in Oman, compared to other countries.
Patients and Methods: A retrospective analysis of premature neonates born with gestational age (GA) 24–32 weeks at Sultan Qaboos University Hospital, Oman, from January 2007 to December 2010. Maternal and neonatal in-hospital course was retrieved. The incidence of ROP was reported. Risk factors analyses were performed using univariate and multivariate statistics.
Results: A total of 171 neonates (57% males, 43% females) were included for analysis. The incidence of ROP (any stage) was 69/171 (40.4%). Infants with ROP had significantly lower GA (27.7±2 weeks) compared to non-ROP group (30.2±1.7 weeks), P < 0.001),P < 0.001) and significantly lower birth weight (BW) (948 ± 242 g in ROP group vs. 1348 ± 283 g in non-ROP group;P < 0.001). Other significant risk factors associated with ROP were: small for GA, respiratory distress syndrome, requirement for ventilation, duration of ventilation or oxygen therapy, bronchopulmonary dysplasia, hyperglycemia, late onset sepsis (clinical or proven), necrotizing enterocolitis, patent ductus arteriosus, seizures, and number of blood transfusions. There was no significant difference in maternal characteristics between the ROP and non-ROP groups except that mothers of infants with ROP were found to be significantly younger. Logistic regression analysis revealed early GA, low BW, duration of Oxygen therapy, and late-onset clinical or proven sepsis as independent risk factors.
Conclusion: ROP is still commonly encountered in neonatal practice in Oman and other countries. Early GA, low BW, and prolonged oxygen therapy continue to be the main risk factors associated with the occurrence of ROP in our setting. In addition, an important preventable risk factor identified in our cohort includes clinical or proven late-onset sepsis. |
topic |
Incidence neonates Oman premature retinopathy of prematurity risk factors |
url |
http://www.ojoonline.org/article.asp?issn=0974-620X;year=2017;volume=10;issue=1;spage=26;epage=32;aulast=Reyes |
work_keys_str_mv |
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