High-throughput sequencing of circRNAs reveals novel insights into mechanisms of nigericin in pancreatic cancer

High-throughput sequencing of circRNAs reveals novel insights into mechanisms of nigericin in pancreatic cancer

Abstract Background Our previous study had proved that nigericin could reduce colorectal cancer cell proliferation in dose- and time-dependent manners by targeting Wnt/β-catenin signaling. To better elucidate its potential anti-cancer mechanism, two pancreatic cancer (PC) cell lines were exposed to...

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Bibliographic Details
Main Authors: Zhihua Xu, Jiaqing Shen, Shangbo Hua, Daiwei Wan, Qian Chen, Ye Han, Rui Ren, Fei Liu, Zhiyong Du, Xiaobo Guo, Jianming Shi, Qiaoming Zhi
Format: Article
Language:English
Published: BMC 2019-09-01
Series:BMC Genomics
Subjects:
Nigericin
High-throughput sequencing
CircRNAs
Mechanism
Pancreatic cancer
Online Access:http://link.springer.com/article/10.1186/s12864-019-6032-3

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