Discovery of potential visfatin activators using in silico docking and ADME predictions as therapy for type 2 diabetes

Discovery of potential visfatin activators using in silico docking and ADME predictions as therapy for type 2 diabetes

Visfatin (Nicotinamide phosphoribosyltransferase) is an adipokine implicated in mediating insulin resistance and exhibiting insulin mimetic effect and therefore represents a druggable target for diabetes therapy. About 3,844 peroxisome proliferator activated receptor gamma (PPARγ) agonists documente...

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Bibliographic Details
Main Authors: Olusola Olalekan Elekofehinti, Oluwamodupe Cecilia Ejelonu, Jean Paul Kamdem, Oluwaseun Benedicta Akinlosotu, Ayodeji Famuti, Damilare Desmond Adebowale, Opeyemi Iwaloye, Yetunde Irinyemi Bulu, Ige Joseph Kade, Joao Batista Teixeira Rocha
Format: Article
Language:English
Published: SpringerOpen 2018-06-01
Series:Beni-Suef University Journal of Basic and Applied Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S2314853517302068

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http://www.sciencedirect.com/science/article/pii/S2314853517302068

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