Discovery of potential visfatin activators using in silico docking and ADME predictions as therapy for type 2 diabetes
Visfatin (Nicotinamide phosphoribosyltransferase) is an adipokine implicated in mediating insulin resistance and exhibiting insulin mimetic effect and therefore represents a druggable target for diabetes therapy. About 3,844 peroxisome proliferator activated receptor gamma (PPARγ) agonists documente...
Main Authors: | Olusola Olalekan Elekofehinti, Oluwamodupe Cecilia Ejelonu, Jean Paul Kamdem, Oluwaseun Benedicta Akinlosotu, Ayodeji Famuti, Damilare Desmond Adebowale, Opeyemi Iwaloye, Yetunde Irinyemi Bulu, Ige Joseph Kade, Joao Batista Teixeira Rocha |
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Format: | Article |
Language: | English |
Published: |
SpringerOpen
2018-06-01
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Series: | Beni-Suef University Journal of Basic and Applied Sciences |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2314853517302068 |
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