MicroRNA-449a delays lung cancer development through inhibiting KDM3A/HIF-1α axis
Abstract Background It has been established that microRNA (miR)-449a is anti-tumorigenic in cancers, including lung cancer. Therefore, this study further explored miR-449a-mediated mechanism in lung cancer, mainly focusing on lysine demethylase 3A/hypoxia-induced factor-1α (KDM3A/HIF-1α) axis. Metho...
Main Authors: | Shan Hu, Peng Cao, Kangle Kong, Peng Han, Yu Deng, Fan Li, Bo Zhao |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-05-01
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Series: | Journal of Translational Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12967-021-02881-8 |
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